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Research uncovers link between wheat bran and cancer prevention
Source: Bakingbusiness.com, August 16, 2004
by Eric Schroeder
MANHATTAN, KAS. - New research from scientists at Kansas State University and Wichita State University suggests that the antioxidant components of wheat may help prevent colorectal cancer tumors.
According to K.S.U., the new research focuses on an antioxidant class of orthophenolics found in wheat bran that appear to block the formation of mutagenic compounds. As part of the initial study, researchers found that diets containing the same level of wheat bran but different levels of antioxidants exhibited dramatically different capacity to suppress tumor development.
In separate studies, researchers at the two universities found that intestinal and colon tumors may be prevented in mice when fed diets supplemented with plant-derived, purified orthophenolics.
"Just think, eating a couple of slices of whole wheat toast each day or adding some wheat bran when shaping a hamburger may be all that it takes to lessen the risks of colorectal cancer," said Ron Madl, a researcher at K.S.U. and director of K.S.U.'s Bioprocessing and Industrial Value-Added Center. "Findings in the study are encouraging, and researchers are now continuing the studies using other animal model systems to test whether these components of wheat can suppress mammary and prostate cancer development."
Mr. Madl noted that while earlier findings have shown whole wheat-based foods are an important part of a balanced diet, the latest study shows that bran antioxidants may play an even more important role in protecting consumers from cancer.
"This work shows the importance of maintaining a balanced diet, including foods from wheat and other cereals that impart the digestive system and protect it against cancer," said Dr. Virgil Smail, head of the Grain Science and Industry Department at K.S.U. "Current restrictive diets may prevent consumers from realizing these health benefits."
Lead researchers on the project include Delores Takemoto of the Department of Biochemistry at K.S.U. and John Carter in the Department of Physical Therapy at W.S.U. Dr. Dennis Lubahn in the Department of Food Science at the University of Missouri will carry out similar research on prostate cancer.
The Kansas Wheat Commission partially funded the research.
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